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Article

DNA diagnosis of Prader-Willi and Angelman syndromes with the probe PW71 (D15S63).

Human genetics - 1 May 1995

van den Ouweland A M, van der Est M N, Wesby-van Swaay E, Tijmensen T S, Los F J, Van Hemel J O, Hennekam R C, Meijers-Heijboer H J, Niermeijer M F, Halley D J

Abstract excerpt

Previously, 158 nuclear families with probands suspected of having either Prader Willi (PWS) or Angelman syndrome (AS) were analyzed with polymorphic DNA markers from the 15q11-13 region. These cases have been re-evaluated with the probe PW71 (D15S63), which detects parent-of-origin-specific alleles after digestion with a methylation-sensitive restriction enzyme (HpaII). Application of PW71 to DNA samples...

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PMID: 7759079
DOI: 10.1007/BF00223870

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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