Article
Molecular and phenotypic spectrum of de novo Philadelphia positive acute leukemia.
International journal of molecular medicine - 1 Dec 1999
Lim L C, Heng K K, Vellupillai M, Tan L T, Boey B C, Lau L C, How G F
Abstract excerpt
The Philadelphia chromosome is present in a heterogeneous group of leukemias. It is most commonly associated with chronic myelogenous leukemia (CML) and B-lineage acute lymphoblastic leukemia (ALL) being found in more than 95% and 15-25% of cases respectively. We undertook a study to determine the morphologic, phenotypic and molecular diversity of Philadelphia positive de novo acute leukemia patients seen at our...
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