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Article

The human herpesvirus-8 ORF 57 gene and its properties

1 Dec 1999

Abstract excerpt

Human herpesvirus-8 (HHV-8) is a gamma(2) lymphotropic herpesvirus associated with Kaposi's sarcoma, a major neoplasm of AIDS patients, and with other AIDS-related neoplasms. The HHV-8 ORF 57 gene is conserved throughout the herpesvirus family and has a herpes simplex virus type 1 homologue, IE63 (also termed ICP27), which is an essential regulatory protein and acts at both transcriptional and...

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PMID: 10567653
DOI: 10.1099/0022-1317-80-12-3207

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