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Early Entry and Widespread Cellular Involvement of HIV-1 DNA in Brains of HIV-1 Positive Asymptomatic Individuals

1 Nov 1999

Abstract excerpt

There is overwhelming evidence that invasion of the central nervous system (CNS) by HIV-1 takes place at an early stage of the infection. It has been demonstrated that HIV-1 DNA is present in brains of asymptomatic individuals. Evidence of immune activation and increased expression of cytokines suggested that neuropathological changes and neuronal and axonal damage could be the effect of the presence of the...

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PMID: 10560658
DOI: 10.1097/00005072-199911000-00005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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