Article
Genetic studies of autistic disorder and chromosome 7.
Genomics - 1 Nov 1999
Ashley-Koch A, Wolpert C M, Menold M M, Zaeem L, Basu S, Donnelly S L, Ravan S A, Powell C M, Qumsiyeh M B, Aylsworth A S, Vance J M, Gilbert J R, Wright H H, Abramson R K, DeLong G R, Cuccaro M L, Pericak-Vance M A
Abstract excerpt
Genome-wide scans have suggested that a locus on 7q is involved in the etiology of autistic disorder (AD). We have identified an AD family in which three sibs inherited from their mother a paracentric inversion in the chromosome 7 candidate region (inv(7)(q22-q31.2)). Clinically, the two male sibs have AD, while the female sib has expressive language disorder. The mother carries the inversion, but does not...
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