Article
p53, c-erbB, and Ki-67 expression in ovaries removed prophylactically from women with a family history of ovarian cancer.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists - 1 Oct 1999
Werness B A, Afify A M, Eltabbakh G H, Huelsman K, Piver M S, Paterson J M
Abstract excerpt
Prophylactically removed ovaries from 64 women were compared with those from 30 women with no known family history of ovarian cancer for expression of the p53 tumor suppressor protein, the c-erbB-2 oncoprotein, and for the proliferation antigen Ki-67. All analyses were performed without knowledge of the family history. Ki-67 was expressed in rare nuclei in both the surface and cyst epithelial cells, whereas p53...
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