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Article

Rapid epithelial-sheet sealing in the Caenorhabditis elegans embryo requires cadherin-dependent filopodial priming.

Current biology : CB - 21 Oct 1999

Raich W B, Agbunag C, Hardin J

Abstract excerpt

BACKGROUND: During embryonic development, epithelia with free edges must join together to create continuous tissues that seal the interior of the organism from the outside environment; failure of epithelial sealing underlies several common human birth defects. Sealing of epithelial sheets in embryos can be extremely rapid, dramatically exceeding the rate of adherens junction formation by epithelial cells in...

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PMID: 10531027
DOI: 10.1016/S0960-9822(00)80015-9

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