Article
Characterization of the MEN1 ortholog in zebrafish.
Biochemical and biophysical research communications - 22 Oct 1999
Khodaei S, O'Brien K P, Dumanski J, Wong F K, Weber G
Abstract excerpt
Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant syndrome predisposing to multiple tumors. The responsible gene, MEN1, has been identified and inactivating mutations reported. It encodes a protein named menin, which lacks homology to any known proteins. Comparative genomics is used to ascertain important functional domains via the identification of evolutionary conserved regions. Here we report...
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