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Factor V Leiden in patients with acute coronary syndromes.

Annali italiani di medicina interna : organo ufficiale della Societa italiana di medicina interna - 1 Jan 2000

Durante Mangoni E, Davies G J, Tuddenham E G, Ruggiero G

Abstract excerpt

A common mutation in coagulation factor V gene gives rise to factor V Leiden, which is resistant to the proteolytic activity of activated protein C. This mutation is known to be a major inherited risk factor for venous thrombosis. In order to investigate the possible pathogenetic role of factor V Leiden in coronary thrombosis, we screened patients with acute ischemic heart disease for this genetic mutation. We...

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PMID: 10528420

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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