Article
The molecular basis of human hypogonadotropic hypogonadism.
Molecular genetics and metabolism - 1 Oct 1999
Layman L C
Abstract excerpt
Patients with hypogonadotropic hypogonadism (HH) present with delayed puberty, infertility, and low serum gonadotropins. The molecular basis for most cases of HH is unknown, but single gene mutations have been described for some hypothalamic and pituitary genes. Kallmann syndrome due to KAL gene mutations and adrenal hypoplasia congenita/HH caused by AHC gene mutations are both X-linked recessive disorders....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.