Independent effects of Apo E phenotype and plasma triglyceride on lipoprotein particle sizes in the fasting and postprandial states.

doi:10.1161/01.atv.19.10.2465

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Article

Independent effects of Apo E phenotype and plasma triglyceride on lipoprotein particle sizes in the fasting and postprandial states.

Arteriosclerosis, thrombosis, and vascular biology - 1 Oct 1999

Dart A M, Cooper B

Abstract excerpt

LDL particle sizes and Apo E phenotypes were determined in 212 subjects of whom 51 had angina. LDL diameter was significantly less in subjects with an epsilon2 allele (24.76+/-0.08 vs 24.94+/-0.02 nm, P=0.02), and this was evident for both E2/E3 (24.77+/-0.09 nm) and E2/E4 (24.69+/-0.08 nm) phenotypes. Although there was a negative relation between LDL diameter and plasma triglyceride, the effect of apo E2 was...

Topics

Alleles
Apolipoprotein E2
Apolipoprotein E4
Apolipoproteins E
Cholesterol, HDL
Cholesterol, LDL
Coronary Disease
Fasting
Female
Humans
Male
Middle Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Particle Size

Phenotype

Postprandial Period

Regression Analysis

Sex Factors

Triglycerides

Source

Open in PubMed

Identifiers

PMID: 10521377
DOI: 10.1161/01.atv.19.10.2465

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