Article
Lung cancer risk in families of nonsmoking probands: heterogeneity by age at diagnosis.
Genetic epidemiology - 1 Nov 1999
Yang P, Schwartz A G, McAllister A E, Swanson G M, Aston C E
Abstract excerpt
In an earlier investigation, we did not detect a major genetic component to lung cancer in families of nonsmoking lung cancer probands. However, heterogeneity with respect to familial aggregation, based on probands' age at diagnosis, was evident. We reanalyzed our previously collected data of 257 families, stratified by age at diagnosis of the probands, using complex segregation analysis. We specifically tested...
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