Article
DNA profiling reveals remarkably low genetic variability in a herd of SLA homozygous pigs.
Research in veterinary science - 1 Oct 1999
Signer E N, Jeffreys A J, Licence S, Miller R, Byrd P, Binns R
Abstract excerpt
Inbred strains of rodents have become indispensable for a wide range of biological studies. It has generally been accepted that genetic uniformity is unlikely to be achieved before 20 generations of brother x sister matings discouraging attempts to inbreed larger mammals. Nevertheless, pigs, homozygous for the swine MHC haplotype SLA b/b, have been inbred at the Babraham Institute for almost thirty years and used...
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