Article
Microsatellite instability assessment in prediction of drug resistance in childhood Burkitt's and large cell diffuse malignant non-Hodgkin lymphoma (MNHL).
Advances in experimental medicine and biology - 1 Jan 1999
Yhap M, Pyesmany A F, Ball L M, Riddle D C, Mu J, van Velzen D
Abstract excerpt
BACKGROUND: Genomic instability may, especially with DNA directed treatment, be associated with increased therapeutic response; absence may be associated with drug resistance. In childhood MNHL, drug response is variable. At present the degree of presence of microsatellite variation, i.e., intrinsic DNA instability is not known. AIMS: To determine presence and range of microsatellite variability in common...
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