Article
Motif-specific probes identify individual genes and detect somatic mutations.
Molecular immunology - 1 Jun 1999
Glas A M, Huang S C, van Montfort E H, Milner E C
Abstract excerpt
This report describes the correlation between motif-specific hybridization and nucleotide sequence as an approach to the identification of individual human V(H) genes using motif-specific oligonucleotide probes, complementary to specific motifs within individual V(H) genes. The sensitivity of the hybridization and post washing processes permits discrimination of single nucleotide differences between probe and...
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