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Article

Mutational analysis of the cardiac actin gene in familial and sporadic dilated cardiomyopathy.

American journal of medical genetics - 8 Oct 1999

Takai E, Akita H, Shiga N, Kanazawa K, Yamada S, Terashima M, Matsuda Y, Iwai C, Kawai K, Yokota Y, Yokoyama M

Abstract excerpt

Dilated cardiomyopathy (DCM) results in part from genetic disorders. Recently, missense mutations of the cardiac actin gene have been reported to cause DCM. We studied 136 Japanese DCM cases to elucidate how frequently the gene mutations are involved in its pathogenesis. Genomic DNA samples were obtained from 136 DCM cases (107 males, 29 females), containing 30 familial DCM (5 confirmed and 25 suspected). All six...

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Identifiers

PMID: 10494087
DOI: 10.1002/(sici)1096-8628(19991008)86:4<325::aid-ajmg5>3.0.co;2-u

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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