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Article

Estrogen receptor polymorphism predicts the onset of natural and surgical menopause.

The Journal of clinical endocrinology and metabolism - 1 Sept 1999

Weel A E, Uitterlinden A G, Westendorp I C, Burger H, Schuit S C, Hofman A, Helmerhorst T J, van Leeuwen J P, Pols H A

Abstract excerpt

Age at menopause and risk of hysterectomy have strong genetic components, but the genes involved remain ill defined. We investigated whether genetic variation at the estrogen receptor (ER) gene contributes to the variability in the onset of menopause in 900 postmenopausal women, aged 55-80 yr, of the Rotterdam Study, a population-based cohort study in The Netherlands. Gynecological information was obtained, and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 10487678
DOI: 10.1210/jcem.84.9.5981

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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