Article
The ABCR gene in recessive and dominant Stargardt diseases: a genetic pathway in macular degeneration.
Genomics - 1 Sept 1999
Zhang K, Kniazeva M, Hutchinson A, Han M, Dean M, Allikmets R
Abstract excerpt
Stargardt disease (STGD) is a juvenile-onset macular dystrophy and can be inherited in an autosomal recessive or in an autosomal dominant manner. Genes involved in dominant STDG have been mapped to human chromosomes 13q (STGD2) and 6q (STGD3). Here, we identify a new kindred with dominant STGD and demonstrate genetic linkage to the STGD3 locus. Because of a more severe macular degeneration phenotype of one of the...
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