Article
Association of a variant of the angiotensinogen gene with pure type of hypertension in pregnancy in the Japanese: implication of a racial difference and significance of an age factor.
American journal of medical genetics - 17 Sept 1999
Kobashi G, Hata A, Shido K, Kato E H, Yamada H, Fujimoto S, Kishi R, Kondo K
Abstract excerpt
The contribution of genetic factors to hypertension in pregnancy, including pre-eclampsia, has been well documented. The association with a common molecular variant of the angiotensinogen (AGT) gene, in which methionine (M235) is substituted for threonine (T235) at residue 235, has been reported in both Caucasians and Japanese. In the present study, we examined 115 cases of pure type of hypertension in pregnancy...
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