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Article

The Molecular Perspective: Methotrexate

1 Sept 1999

Abstract excerpt

Chemotherapy is the art of selective poisoning. Many of the poisons used in modern chemotherapy rely on the observation that most cells in the body are not actively dividing, so substances that block some step in cell reproduction will have a disproportionately severe effect on growing cancer cells relative to most healthy tissues. Virtually every step of cell growth and division is targeted by some...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 10476546
DOI: 10.1002/stem.170314

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