Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The pathophysiological and molecular basis of Bartter's and Gitelman's syndromes.

Postgraduate medical journal - 1 Jul 1999

Bhandari S

Abstract excerpt

Molecular defects affecting the transport of sodium, potassium and chloride in the nephron through the ROMK K+ channel, Na+/K+/2Cl- cotransporter, the Na+/Cl- cotransporter and chloride channel have been identified in patients with Bartter's and Gitelman's syndromes. Defects of the angiotensin II type I receptor and CFTR have also being described. These defects are simple (i.e., most are single amino acid...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chlorides
Share to Hypokalemia
Share to Kidney Tubules

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Receptors, Drug

Share to Sodium Chloride Symporters

Share to Sodium-Potassium-Chloride Symporters

Share to Solute Carrier Family 12, Member 3

Share to Symporters

Source

Open in PubMed Open full text

Identifiers

PMID: 10474721
DOI: 10.1136/pgmj.75.885.391
PMCID: PMC1741279

Genes

CFTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The pathophysiological and molecular basis of Bartter's and Gitelman's syndromes.PMID 10474721Read ↗

Ion transporter mutations in Gitelman's and Bartter's syndromes.Semantic proximity Read ↗

Mutations in Na(K)Cl transporters in Gitelman's and Bartter's syndromes.Semantic proximity Read ↗

Molecular pathophysiology of Bartter's and Gitelman's syndromes.Semantic proximity Read ↗

Bartter's and Gitelman's syndromes: from gene to clinic.Semantic proximity Read ↗

Future considerations based on the information from Barrter's and Gitelman's syndromes.Semantic proximity Read ↗

Understanding Bartter syndrome and Gitelman syndrome.Semantic proximity Read ↗

The molecular genetic approach to "Bartter's syndrome".Semantic proximity Read ↗

Bartter and Gitelman syndromes: Questions of class.Semantic proximity Read ↗

Bartter's and Gitelman's syndrome.Semantic proximity Read ↗

Mutations in renal ion transporters cause Gitelman's and Bartter's syndromes of inherited hypokalemic alkalosis.Semantic proximity Read ↗

Cystic Fibrosis Presenting as Pseudo-Bartter Syndrome: An Important Diagnosis that is Missed!Semantic proximity Read ↗

A novel mutation in the chloride channel gene, CLCNKB, as a cause of Gitelman and Bartter syndromes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.