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Article

Radiation-induced changes in nucleotide metabolism of two colon cancer cell lines with different radiosensitivities

1 Jan 1999

Abstract excerpt

PURPOSE: To investigate changes in nucleotide metabolism after irradiation. MATERIALS AND METHODS: HT29 and SW48 human colon carcinoma cells were exposed to 60Co gamma-rays at doses ranging from 0 to 7.5 Gy. At different times after irradiation, the activities of nine enzymes involved in nucleotide metabolism were measured, the levels of thymidine kinase and deoxycytidine kinase proteins were evaluated by Western...

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PMID: 10465366
DOI: 10.1080/095530099139764

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