Article
The potential of molecular screening.
Surgical oncology clinics of North America - 1 Oct 1999
Ahrendt S A, Sidransky D
Abstract excerpt
Clonal genetic alterations such as tumor suppressor, gene mutations, or microsatellite instability are a hallmark of human cancer. These genetic alterations can be detected in clinical samples using DNA amplification techniques and used for early detection of cancer. This article reviews molecular-based approaches for screening of malignancies commonly encountered by the practicing general surgeon.
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