Article
Epstein-Barr virus genomes are found predominantly in IgA-positive B cells in the blood of healthy carriers.
International journal of cancer - 24 Sept 1999
Ehlin-Henriksson B, Zou J Z, Klein G, Ernberg I
Abstract excerpt
B lymphocytes have been identified as the main reservoir of latent Epstein-Barr virus (EBV) in healthy virus carriers. We have established a semi-quantitative PCR method to estimate the EBV genome load in the blood B-cell subpopulation in healthy individuals. EBV DNA was detected in subfractionated IgM-, IgG- and IgA-positive B cells. Between 80% and 90% of the viral DNA was found in the IgA-positive compared...
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