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Article

Serum induction of the collagen X promoter requires the Raf/MEK/ERK and p38 pathways.

Biochemical and biophysical research communications - 19 Aug 1999

Beier F, LuValle P

Abstract excerpt

The collagen X gene is expressed exclusively by differentiated, hypertrophic chondrocytes. The mechanisms controlling collagen X expression remain largely unknown. Here we show that collagen X promoter activity can be induced by serum stimulation of chondrogenic MCT cells. The serum response is conferred by a 462 nucleotide promoter fragment. Both the c-Raf/MEK/ERK and p38 MAP kinase pathways are required for...

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Identifiers

PMID: 10448066
DOI: 10.1006/bbrc.1999.1178

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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