Article
Hepatocellular mitochondrial alterations in patients with chronic hepatitis C: ultrastructural and biochemical findings.
The American journal of gastroenterology - 1 Aug 1999
Barbaro G, Di Lorenzo G, Asti A, Ribersani M, Belloni G, Grisorio B, Filice G, Barbarini G
Abstract excerpt
OBJECTIVE: Hepatitis C virus (HCV) infection is associated with increased lipoperoxidation, which may lead to interference with mitochondrial function with possible depletion of mitochondrial DNA (mtDNA). We correlated the ultrastructural findings of liver biopsy specimens with the lipoperoxidation markers and contents of mtDNA in chronic hepatitis C (CHC) patients with a different HCV genotype. METHODS: Liver...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
