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Article

New Concepts on the Role of Human Papillomavirus in Cell Cycle Regulation

1 Jan 1999

Abstract excerpt

Human papillomaviruses (HPVs) are strictly host-specific and also show a distinct tropism to squamous epithelial cells. Upon HPV infection, only a portion of the virus reaching the nucleus seems to undergo replication, suggesting that HPV replication remains confined to a small number of cells. HPVs critically depend on the cellular machinery for the replication of their genome. Viral replication is restricted to...

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PMID: 10442672
DOI: 10.3109/07853899909115976

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