Article
[Molecular basis of oncogenesis induced by human papilloma viruses].
Voprosy onkologii - 1 Jan 2012
Korita P V, Trotsenko O E, Annenkov A Iu, Filimonov V V
Abstract excerpt
Human papilloma viruses (HPV) of high carcinogenesis risk play important role in development of cancer of oropharyngeal and anogenital areas. Possible malignant transformation of cells, infected by HPV, is due to the expression of three proteins, E6, E7 and E5. These proteins mostly influence on mechanisms that regulate cellular cycle, proliferation and apoptosis inducing and maintaining oncogenesis. This review...
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