Article
The gene for leukoencephalopathy with vanishing white matter is located on chromosome 3q27.
American journal of human genetics - 1 Sept 1999
Leegwater P A, Könst A A, Kuyt B, Sandkuijl L A, Naidu S, Oudejans C B, Schutgens R B, Pronk J C, van der Knaap M S
Abstract excerpt
Leukoencephalopathy with vanishing white matter (VWM) is an autosomal recessive disorder with normal early development and, usually, childhood-onset neurological deterioration. At present, diagnosis of VWM is based on clinical examination and the results of repeat magnetic resonance imaging and magnetic resonance spectroscopy, which show that, with time, increasing amounts of the cerebral white matter vanish and...
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