Article
Effects on the Ciliated Epithelium of Protein D–Producing and –Nonproducing NontypeableHaemophilus influenzaein Nasopharyngeal Tissue Cultures
1 Sept 1999
Abstract excerpt
A pair of isogenic, nontypeable Haemophilus influenzae strains, one expressing protein D and the other protein D-negative, was compared in their ability to cause damage in a human nasopharyngeal tissue culture model. Damage was assessed by measuring the ciliary beat frequency (CBF) of tissue specimens at 12 h intervals. Cultures inoculated with H. influenzae manifested a decrease in CBF beginning after 12 h, with...
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