Article
[Alpha 1-protease inhibitor deficiency. Diagnosis, follow-up and therapy options].
Medizinische Klinik (Munich, Germany : 1983) - 15 Jul 1999
Köhnlein T, Klein H, Welte T
Abstract excerpt
DEFINITION: Alpha-1 antitrypsin (alpha-1 proteinase inhibitor) deficiency is characterized by a marked reduction of alpha-1 antitrypsin, the major antiprotease in man. PREVALENCE: Alpha-1 antitrypsin deficiency is one of the most common hereditary diseases in Caucasians of European descent. Alpha-1 antitrypsin deficiency is the underlying disorder in approximately 2% of all patients with chronic obstructive...
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