Article
Type III collagen deficiency in saccular intracranial aneurysms. Defect in gene regulation?
Stroke - 1 Aug 1999
van den Berg J S, Pals G, Arwert F, Hennekam R C, Albrecht K W, Westerveld A, Limburg M
Abstract excerpt
BACKGROUND AND PURPOSE: We sought to determine whether there are mutations in the COL3A1 gene in patients with saccular intracranial aneurysms with a type III collagen deficiency and whether there is an association between a marker in the COL3A1 gene and saccular intracranial aneurysms. One of the heritable factors possibly involved in the pathogenesis of saccular intracranial aneurysms is a reduced production of...
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