Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

At least three genes account for familial papillary thyroid carcinoma: TCO and MNG1 excluded as susceptibility loci from a large Tasmanian family.

European journal of endocrinology - 1 Aug 1999

McKay J D, Williamson J, Lesueur F, Stark M, Duffield A, Canzian F, Romeo G, Hoffman L

Abstract excerpt

Recent studies have mapped two susceptibility loci which appear to account for familial multinodular goitre (MNG1) and a variant of familial papillary thyroid cancer (PTC), with associated multinodular goitre (TCO). A Tasmanian family (Tas1) has been identified with an autosomal dominant form of PTC. This study has examined the MNG1 and TCO loci to determine if they are similarly predisposing the Tas1 family to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Papillary
Share to TSHR gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Linkage

Share to Genetic Predisposition to Disease

Share to Microsatellite Repeats

Share to Pedigree

Share to Tasmania

Share to Thyroid Neoplasms

Source

Identifiers

PMID: 10427154
DOI: 10.1530/eje.0.1410122

Genes

APC
MET
PTEN
RET
TSHR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

At least three genes account for familial papillary thyroid carcinoma: TCO and MNG1 excluded as susceptibility loci from a large Tasmanian family.PMID 10427154Read ↗

A Greek family with a follicular variant of familial papillary thyroid carcinoma: TCO, MNG1, fPTC/PRN, and NMTC1 excluded as susceptibility loci.Semantic proximity Read ↗

A comprehensive analysis of MNG1, TCO1, fPTC, PTEN, TSHR, and TRKA in familial nonmedullary thyroid cancer: confirmation of linkage to TCO1.Semantic proximity Read ↗

Familial papillary thyroid carcinoma: genetics, criteria for diagnosis, clinical features, and surgical treatment.Semantic proximity Read ↗

Papillary Thyroid Carcinoma Associated with Papillary Renal Neoplasia: Genetic Linkage Analysis of a Distinct Heritable Tumor Syndrome*Semantic proximity Read ↗

Two families with an autosomal dominant inheritance pattern for papillary carcinoma of the thyroid.Semantic proximity Read ↗

Genetic predisposition to papillary thyroid cancer.Semantic proximity Read ↗

A new form of familial multi-nodular goitre with progression to differentiated thyroid cancer.Semantic proximity Read ↗

Genetic heterogeneity in familial nonmedullary thyroid carcinoma: exclusion of linkage to RET, MNG1, and TCO in 56 families. NMTC Consortium.Semantic proximity Read ↗

A Germline Mutation (A339V) in Thyroid Transcription Factor-1 (TITF-1/NKX2.1) in Patients With Multinodular Goiter and Papillary Thyroid CarcinomaSemantic proximity Read ↗

Familial non-medullary thyroid carcinoma (FNMTC): analysis of fPTC/PRN, NMTC1, MNG1 and TCO susceptibility loci and identification of somatic BRAF and RAS mutations.Semantic proximity Read ↗

Familial Papillary Thyroid Cancer—Many Syndromes, Too Many Genes?*Semantic proximity Read ↗

Mapping a new familial thyroid epithelial neoplasia susceptibility locus to chromosome 8p23.1-p22 by high-density single-nucleotide polymorphism genome-wide linkage analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.