Article
Mutations in CCR5-coding sequences are not associated with SIV carrier status in African nonhuman primates.
AIDS research and human retroviruses - 1 Jul 1999
Müller-Trutwin M C, Corbet S, Hansen J, Georges-Courbot M C, Diop O, Rigoulet J, Barré-Sinoussi F, Fomsgaard A
Abstract excerpt
African monkeys can be naturally infected with SIV but do not progress to AIDS. Since mutations in the human CCR5 gene have been shown to influence susceptibility to HIV infection and disease progression, we have now investigated whether mutations in CCR5-coding sequences in African nonhuman primates can explain species-specific differences in susceptibility to lentiviral infection. The animals studied comprise...
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