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Article

Mutation of the Na-K-Cl co-transporter gene Slc12a2 results in deafness in mice.

Human molecular genetics - 1 Aug 1999

Dixon M J, Gazzard J, Chaudhry S S, Sampson N, Schulte B A, Steel K P

Abstract excerpt

Hearing impairment is a common human condition, but we know little about the molecular basis of cochlear function. Shaker-with-syndactylism (sy) is a classic deaf mouse mutant and we show here that a second allele, sy(ns), is associated with abnormal production of endolymph, the fluid bathing sen...

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Source

Identifiers

PMID: 10401008
DOI: 10.1093/hmg/8.8.1579

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-10401008-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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