Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hb Iraq-Halabja beta10 (A7) Ala-->Val (GCC-->GTC): a new beta-chain silent variant in a family with multiple Hb disorders.

American journal of hematology - 1 Jul 1999

Deutsch S, Darbellay R, Offord R, Frutiger A, Kister J, Wajcman H, Beris P

Abstract excerpt

A patient originating from Iraq was referred to our laboratory upon suspicion of a hemoglobinopathy. Routine hematological tests revealed a microcytic and slightly anemic phenotype with an elevated HbA2 suggestive of beta-thalassemia. Samples were obtained for several members of the family which upon examination revealed highly heterogeneous phenotypes that prompted us to investigate the case further. Sequencing...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alanine
Share to Globins
Share to Hemoglobinopathies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Hemoglobins, Abnormal

Share to Macromolecular Substances

Share to Point Mutation

Share to Protein Structure, Secondary

Share to Valine

Source

Identifiers

PMID: 10398311
DOI: 10.1002/(sici)1096-8652(199907)61:3<187::aid-ajh5>3.0.co;2-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hb Iraq-Halabja beta10 (A7) Ala-->Val (GCC-->GTC): a new beta-chain silent variant in a family with multiple Hb disorders.PMID 10398311Read ↗

Hb SKMC and an unprecedented γδβ-thalassemia: first report from Iraq.Semantic proximity Read ↗

Molecular Characterization of β-Thalassemia in the Dohuk Region of IraqSemantic proximity Read ↗

Hemoglobin Cagliari (beta 60 [E4] Val----Glu): a novel unstable thalassemic hemoglobinopathy.Semantic proximity Read ↗

Molecular Basis of β-Thalassemia Intermedia in Erbil Province of Iraqi Kurdistan.Semantic proximity Read ↗

Molecular characterization of alpha-thalassemia in the Dohuk region of Iraq.Semantic proximity Read ↗

Hb Groene Hart: a new Pro-->Ser amino acid substitution at position 119 of the alpha1-globin chain is associated with a mild alpha-thalassemia phenotype.Semantic proximity Read ↗

Hb Campinas [alpha26(B7)Ala -->Val]: a novel, electrophoretically silent, variant.Semantic proximity Read ↗

Hb Adana or alpha 2(59)(E8)Gly-->Asp beta 2, a severely unstable alpha 1-globin variant, observed in combination with the -(alpha)20.5 Kb alpha-thal-1 deletion in two Turkish patients.Semantic proximity Read ↗

New and known β-thalassemia determinants masked by known and new δ gene defects [Hb A(2)-Ramallah or δ6(A3)Glu→Gln, GAG>>CAG].Semantic proximity Read ↗

A Clinical Update of the Hb Siirt [β27(B9)Ala→Gly; HBB: c.83C>G] Hemoglobin Variant.Semantic proximity Read ↗

Genetic heterogeneity of Beta thalassemia in Lebanon reflects historic and recent population migration.Semantic proximity Read ↗

Hb Lansing (HBA2: c.264C > G) and a new β promoter transversion [-52 (G > T)]: an attempt to define the phenotype of two mutations found in the Omani population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.