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Article

Evidence for recombination in natural populations of dengue virus type 1 based on the analysis of complete genome sequences

1 Jun 2001

Abstract excerpt

Recombination events are known to occur in non-segmented RNA viruses like polioviruses or alphaviruses. Analysis of the subgenomic sequences of dengue virus type 1 (DENV-1) structural genes has recently allowed the identification of possible recombination breakpoints. Because DENV is a major human pathogen, this discovery might have important implications for virus pathogenicity, vaccine safety and efficiency, or...

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PMID: 11369871
DOI: 10.1099/0022-1317-82-6-1283

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