Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gene structure, chromosomal location, and expression pattern of maleylacetoacetate isomerase.

Genomics - 15 Jun 1999

Fernández-Cañón J M, Hejna J, Reifsteck C, Olson S, Grompe M

Abstract excerpt

The gene for maleylacetoacetate isomerase (MAAI) (EC 5.2.1.2) was the last gene in the mammalian phenylalanine/tyrosine catabolic pathway to be cloned. We have isolated the human and murine genes and determined their genomic structure. The human gene spans a genomic region of approximately 10 kb, has 9 exons ranging from 50 to 528 bp in size, and was mapped to 14q24.3-14q31.1 using fluorescence in situ...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Metabolism, Inborn Errors
Share to Blotting, Northern
Share to Chromosome Banding

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 14

Share to cis-trans-Isomerases

Share to Tissue Distribution

Share to Tyrosine

Source

Identifiers

PMID: 10373324
DOI: 10.1006/geno.1999.5832

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gene structure, chromosomal location, and expression pattern of maleylacetoacetate isomerase.PMID 10373324Read ↗

Characterization of a Fungal Maleylacetoacetate Isomerase Gene and Identification of Its Human HomologueSemantic proximity Read ↗

Functional characterization of the TMLH gene: promoter analysis, in situ hybridization, identification and mapping of alternative splicing variants.Semantic proximity Read ↗

Structural organization and analysis of the human fumarylacetoacetate hydrolase gene in tyrosinemia type I.Semantic proximity Read ↗

Characterization of the human fumarylacetoacetate hydrolase gene and identification of a missense mutation abolishing enzymatic activity.Semantic proximity Read ↗

Multiple effects on liver-specific gene expression in albino lethal mice caused by deficiency of an enzyme in tyrosine metabolism.Semantic proximity Read ↗

A murine model for type III tyrosinemia: lack of immunologically detectable 4-hydroxyphenylpyruvic acid dioxygenase enzyme protein in a novel mouse strain with hypertyrosinemia.Semantic proximity Read ↗

Cloning and expression of murine S-adenosylmethionine synthetaseSemantic proximity Read ↗

Deficiency of an enzyme of tyrosine metabolism underlies altered gene expression in newborn liver of lethal albino mice.Semantic proximity Read ↗

Identification of two novel mutations in the methylmalonyl-CoA mutase gene with decreased levels of mutant mRNA in methylmalonic acidemia.Semantic proximity Read ↗

Mapping of ornithine aminotransferase gene sequences to mouse chromosomes 7, X, and 3.Semantic proximity Read ↗

Localization, structure and polymorphism of two paralogous Xenopus laevis mitochondrial malate dehydrogenase genes.Semantic proximity Read ↗

Loss of fumarylacetoacetate hydrolase is responsible for the neonatal hepatic dysfunction phenotype of lethal albino mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.