Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phenotypic variation in dentinogenesis imperfecta/dentin dysplasia linked to 4q21.

Journal of dental research - 1 Apr 2006

Beattie M L, Kim J-W, Gong S-G, Murdoch-Kinch C A, Simmer J P, Hu J C-C

Abstract excerpt

Dentinogenesis imperfecta (DGI) and dentin dysplasia (DD) are allelic disorders that primarily affect the formation of tooth dentin. Both conditions are autosomal-dominant and can be caused by mutations in the dentin sialophosphoprotein gene (DSPP, 4q21.3). We recruited 23 members of a four-generation kindred, including ten persons with dentin defects, and tested the hypothesis that these defects are linked to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomes, Human, Pair 4
Share to Dentin
Share to Dentinogenesis Imperfecta

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Extracellular Matrix Proteins

Share to Glycoproteins

Share to Phosphoproteins

Share to Severity of Illness Index

Share to Sialoglycoproteins

Source

Open in PubMed Open full text

Identifiers

PMID: 16567553
DOI: 10.1177/154405910608500409
PMCID: PMC2238637

Genes

DSPP
DMP1
DSP
MEPE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phenotypic variation in dentinogenesis imperfecta/dentin dysplasia linked to 4q21.PMID 16567553Read ↗

Dentin dysplasia type I—A dental disease with genetic heterogeneitySemantic proximity Read ↗

Molecular basis of human dentin diseases.Semantic proximity Read ↗

Phenotype characterization and DSPP mutational analysis of three Brazilian dentinogenesis imperfecta type II families.Semantic proximity Read ↗

Phenotype and genotype analyses in seven families with dentinogenesis imperfecta or dentin dysplasia.Semantic proximity Read ↗

Dental properties, ultrastructure, and pulp cells associated with a novel DSPP mutation.Semantic proximity Read ↗

Dentinogenesis imperfecta type II- genotype and phenotype analyses in three Danish families.Semantic proximity Read ↗

Enamel malformations associated with a defined dentin sialophosphoprotein mutation in two families.Semantic proximity Read ↗

A novel DSPP mutation causes dentinogenesis imperfecta type II in a large Mongolian family.Semantic proximity Read ↗

Hereditary dentine disorders: dentinogenesis imperfecta and dentine dysplasiaSemantic proximity Read ↗

Hereditary dentin defects.Semantic proximity Read ↗

Inherited dentin defects with comorbidities.Semantic proximity Read ↗

Identification of DSPP Novel Variants and Phenotype Analysis in dentinogenesis dysplasia shields type II PatientsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.