Article
Relationship between U83 gene variation in human herpesvirus 6 and secretion of the U83 gene product.
Archives of virology - 1 Jan 2009
Sjahril R, Isegawa Yuji, Tanaka T, Nakano K, Yoshikawa T, Asano Y, Ohshima A, Yamanishi K, Sugimoto N
Abstract excerpt
The betaherpesvirus human herpesvirus 6 (HHV-6) has two variants. The U83 gene product of strain HST is a chemoattractant for monocytes. Here, we describe U83 gene variations that accumulated in variants A and B. A gene-variation hot spot was examined in 36 different strains and one donor DNA sample. U83 gene variations accumulated in variant A and in reactivated variant B after transplantation. None of the...
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