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Germline hMSH2 and differential somatic mutations in patients with Turcot's syndrome.

Genes, chromosomes & cancer - 1 Jun 1999

Chan T L, Yuen S T, Chung L P, Ho J W, Kwan K, Fan Y W, Chan A S, Leung S Y

Abstract excerpt

Turcot's syndrome is characterized clinically by the occurrence of primary brain tumor and colorectal tumor and has in previous reports been shown to be associated with germline mutations in the genes APC, hMLH1, and hPMS2. Here we describe three patients with Turcot's syndrome, each having colorectal adenocarcinoma and malignant glioma. All the colorectal and brain tumors from these patients showed replication...

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PMID: 10337989

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BAX
APC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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