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Article

Turcot syndrome confirmed with molecular analysis.

European journal of neurology - 1 Apr 2007

Lebrun C, Olschwang S, Jeannin S, Vandenbos F, Sobol H, Frenay M

Abstract excerpt

Turcot syndrome is clinically characterized by the occurrence of primary brain tumor and colorectal tumor and has, in previous reports, been shown associated with germline mutations in the genes APC, MLH1, MHS6, and PMS2. To date, only few families have been documented by molecular analysis. We report two new families with Turcot syndrome to illustrate and review its characteristics and facilitate diagnosis....

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Source

Identifiers

PMID: 17389002
DOI: 10.1111/j.1468-1331.2006.01669.x

Genes

MLH1
APC
MSH2
PMS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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