Article
A constitutively active G-protein-coupled receptor causes mating self-compatibility in the mushroom Coprinus.
The EMBO journal - 17 May 1999
Olesnicky N S, Brown A J, Dowell S J, Casselton L A
Abstract excerpt
In the mushroom Coprinus cinereus, the multiallelic B mating type genes are predicted to encode a large family of seven-transmembrane domain receptors and CaaX-modified pheromones. We have shown that a single amino acid change Q229P in transmembrane domain VI of one receptor confers a self-compatible mating phenotype. Using a heterologous yeast assay, we have demonstrated that this C.cinereus pheromone receptor...
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