Article
No association between DRD2 locus and alcoholism after controlling the ADH and ALDH genotypes in Chinese Han population.
Alcoholism, clinical and experimental research - 1 Apr 1999
Lee J F, Lu R B, Ko H C, Chang F M, Yin S J, Pakstis A J, Kidd K K
Abstract excerpt
BACKGROUND: Recent studies on the genetics of alcoholism have examined the association between alcoholism and the dopamine D2 receptor locus (DRD2); our study of Chinese Han gave negative results (Lu et al., 1996). The different genotypes at the genes encoding the enzymes involved in alcohol metabolism, class one alcohol dehydrogenase (ADH2 and ADH3) and mitochondrial aldehyde dehydrogenase (ALDH2), have...
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