Article
Putative hemochromatosis gene mutations and alcoholic liver disease with iron overload in Japan.
Alcoholism, clinical and experimental research - 1 Apr 1999
Sohda T, Takeyama Y, Irie M, Kamimura S, Shijo H
Abstract excerpt
It is well known that alcoholic liver disease is associated with iron overload. To study the role of hemochromatosis gene mutations on the pathogenesis of alcoholic liver disease (ALD), we have analyzed C282Y and H63D mutations on the chromosomes obtained from 95 Japanese alcoholics. Patients were divided in two groups [i.e., 64 alcoholic patients with liver damage (group I) and 31 alcoholics without liver damage...
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