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Article

Mutational analysis, using a full-length rubella virus cDNA clone, of rubella virus E1 transmembrane and cytoplasmic domains required for virus release.

Journal of virology - 1 Jun 1999

Yao J, Gillam S

Abstract excerpt

We report on the construction of a full-length cDNA clone, pBRM33, derived from wild-type rubella virus M33 strain. The RNA transcripts synthesized in vitro from pBRM33 are highly infectious, and the viruses produced retain the phenotypic characteristics of the parental M33 virus in growth rate and plaque size. This cDNA clone was used to study the role of E1 transmembrane and cytoplasmic domains in virus...

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Identifiers

PMID: 10233921
DOI: 10.1128/JVI.73.6.4622-4630.1999
PMCID: PMC112503

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