Article
Increased prevalence of vitiligo, but no evidence of premature ageing, in the skin of patients with bp 3243 mutation in mitochondrial DNA in the mitochondrial encephalomyopathy, lactic acidosis and stroke-like episodes syndrome (MELAS).
The British journal of dermatology - 1 Apr 1999
Karvonen S L, Haapasaari K M, Kallioinen M, Oikarinen A, Hassinen I E, Majamaa K
Abstract excerpt
The MELAS syndrome (mitochondrial encephalomyopathy, lactic acidosis and stroke-like episodes) belongs to the category of mitochondrial disorders. The most common molecular aetiology of the syndrome is a mutation at base pair (bp) 3243 in the mitochondrial genome (mtDNA). The phenotype is varied and, apart from central nervous system involvement, the patients with this mutation may present with neurosensory...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.