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Article

Identification of new mutations in the hepatocyte nuclear factor 4alpha gene among families with early onset Type 2 diabetes mellitus.

Diabetic medicine : a journal of the British Diabetic Association - 1 Mar 1999

Malecki M T, Yang Y, Antonellis A, Curtis S, Warram J H, Krolewski A S

Abstract excerpt

AIMS: Mutations in hepatocyte nuclear factor (HNF)-4alpha gene located on chromosome 20q have been found to be responsible for the development of early onset Type 2 diabetes mellitus (DM). Through a national campaign, 53 families with autosomal dominant, early onset Type 2 DM (n=654) were assembled to determine the frequency of mutations in the HNF-4alpha gene and their contribution to the development of...

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Identifiers

PMID: 10227563
DOI: 10.1046/j.1464-5491.1999.00073.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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