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Article

Sperm treatment with extracellular ATP increases fertilization rates in in-vitro fertilization for male factor infertility

1 Mar 1999

Abstract excerpt

Previous work from our laboratory has revealed that extracellular ATP is a rapid and potent activator of human sperm acrosome reaction and fertilizing ability. In the present study, we assessed the effects of in-vitro sperm incubation with ATP on fertilization and embryo development in couples undergoing in-vitro fertilization (IVF) for male factor infertility. Oocytes from 22 women undergoing ovulation induction...

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PMID: 10221697
DOI: 10.1093/humrep/14.3.694

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