Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Determination of the Clonal Origin of Multiple Human Hepatocellular Carcinomas by Cloning and Polymerase Chain Reaction of the Integrated Hepatitis B Virus Dna

1 May 1999

Abstract excerpt

The poor prognosis of hepatocellular carcinoma (HCC) is partly the result of the high rate of recurrence that is caused either by intrahepatic metastasis (IM) or independent multicentric occurrence (MO). For convenience, discrimination of IM and MO is based on pathological findings, but reliable parameters are not sufficiently established. In the case of hepatitis B virus (HBV)-associated HCC, molecular...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cholangiocarcinoma and Gallbladder Cancer Studies
Share to Hepatitis B Virus Studies
Share to Hepatocellular Carcinoma Treatment and Prognosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 10216128
DOI: 10.1002/hep.510290523

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 10 closest

Determination of the Clonal Origin of Multiple Human Hepatocellular Carcinomas by Cloning and Polymerase Chain Reaction of the Integrated Hepatitis B Virus DnaPMID 10216128Read ↗

Determination of the molecular relationship between multiple tumour nodules in hepatocellular carcinoma differentiates multicentric origin from intrahepatic metastasisSemantic proximity Read ↗

Clinical utility of clonal origin determination in managing recurrent hepatocellular carcinoma.Semantic proximity Read ↗

Diagnosis of intrahepatic metastasis and multicentric carcinogenesis by microsatellite loss of heterozygosity in patients with multiple and recurrent hepatocellular carcinomasSemantic proximity Read ↗

HBV DNA integration and HBV-transcript expression in non-B, non-C hepatocellular carcinoma in Japan.Semantic proximity Read ↗

Different pattern of chromosomal allele loss in multiple hepatocellular carcinomas as evidence of their multifocal origin.Semantic proximity Read ↗

Mutation pattern of the p53 gene as a diagnostic marker for multiple hepatocellular carcinoma.Semantic proximity Read ↗

Polymerase chain reaction screening of immunoglobulin heavy chain and T cell receptor gamma gene rearrangements: a practical approach to molecular DNA analysis of non-Hodgkin's lymphoma in a surgical pathology laboratory.Semantic proximity Read ↗

Detection of Clonally Expanded Hepatocytes in Chimpanzees with Chronic Hepatitis B Virus InfectionSemantic proximity Read ↗

Structural rearrangement of integrated hepatitis B virus DNA as well as cellular flanking DNA is present in chronically infected hepatic tissuesSemantic proximity Read ↗

Hepatocellular carcinomas infected with the novel TT DNA virus lack viral integration.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.